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But we are proud to say that Bastian Arlt contributed 97 entries already.
MCC pellets under rheological investigation MCC pellets under rheological investigation are ideal model spheres for studying powder behavior. In this study, we revisit the work of V. Mohylyuk and R. Dattani to analyze the effect of pellet size on powder properties. Understanding how pellet size influences flow and handling is essential for optimizing powder performance. […]
Research Advances in MCC Pellet Technology and Applications Scientific literature on MCC pellets highlights the growing importance of CELLETS® in pharmaceutical and scientific research. These microcrystalline cellulose spheres play a key role in developing reliable multiparticulate drug delivery systems. Researchers have investigated improved rivaroxaban dissolution, efficient film coating kinetics, and their use in orally disintegrating […]
Introduction to delayed release oral pharmaceutical compositions Delayed release oral pharmaceutical compositions enable drug delivery at a defined time after oral administration. Unlike immediate release dosage forms, these systems control when the active pharmaceutical ingredient becomes available for absorption. As a result, they protect acid-sensitive drugs and allow targeted delivery to specific gastrointestinal regions. Moreover, […]
Chewable formulations with MCC starter cores: Patient-centric design and pharmaceutical relevance Chewable formulations with MCC starter cores are an advanced oral dosage form that combines patient-friendly administration with robust pharmaceutical performance. Thereby, patient refers includes humans and non-human mammalian animals, such as dogs, cats, mice, rats, guinea pigs, rabbits, ferrets, cows, horses, sheep, goats, and […]
Introduction to soft tabletting of pellets and MCC pellet functionality Soft tabletting of pellets is a specialized pharmaceutical compaction approach that enables the compression of coated pellet subunits into tablets while preserving pellet integrity and drug release performance. In this context, Multiple Unit Pellet Systems, or MUPS, combine the biopharmaceutical advantages of multiparticulates with the […]
Introduction to Particle Size Distributions of Inert Spheres and Their Role in Pelletized Pharmaceutical Products In pharmaceutical formulation science, Particle Size Distributions of Inert Spheres represent a fundamental quality attribute for multiparticulate dosage forms. Inert spheres, such as microcrystalline cellulose pellets, act as neutral carriers for active pharmaceutical ingredients. They enable precise drug layering, predictable […]
CELLETS® Pharmaceutical Starter Cores for Pellets & Functional Coatings CELLETS® are high-purity pharmaceutical starter cores. They combine spherical geometry with narrow particle size distribution and defined density. They provide reproducible carriers for functional coatings and enable controlled layer formation in fluid bed and drum coating processes. Thanks to their uniform geometry, CELLETS® ensure stable fluidization, […]
Introduction to Different Pelletization Techniques and Their Functionality in Drug Formulations Different pelletization techniques form a core part of pharmaceutical manufacturing for solid dosage forms that deliver active pharmaceutical ingredients (APIs) with enhanced performance. Pelletization, a process that generates small, uniform spherical particles, improves flow properties, enables controlled or delayed release, and reduces local irritation […]
Enzyme‑cleavable methadone prodrugs: Functionality, Opportunities, and Summary of US20250361205A1 Introduction to Enzyme‑cleavable methadone prodrugs Enzyme‑cleavable methadone prodrugs represent a novel class of pharmacological agents designed to provide controlled release of methadone only after specific enzymatic activation. These prodrugs attach an enzyme‑cleavable promoiety to the methadone molecule, rendering it inactive until a target enzyme cleaves the […]