Entries by Bastian Arlt

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Patent on pharmaceutical compositions and methods for treating hyperhidrosis

The patent application US20240350420A1 focuses on pharmaceutical formulations and methods for treating conditions such as hyperhidrosis, which involves excessive sweating. The document details the development of modified-release compositions, specifically utilizing Pilocarpine HCl, a muscarinic agonist. These formulations aim to optimize drug delivery by employing various release mechanisms, including immediate, delayed, or sustained release. The innovations […]

21. November 2024 by
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Patent on gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state

Patents US20240350437A1 and US20240350438A1 – Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state – Google Patents relates to pharmaceutical compositions and systems designed to provide controlled and consistent drug release for oral administration. The invention addresses challenges associated with delayed or multi-stage drug delivery, particularly for active pharmaceutical ingredients (APIs) with complex absorption profiles […]

21. November 2024 by

What does AI say about CELLETS?

Did you ever wonder, what AI engines say about CELLETS? Artificial Intelligence engines answers by example of ChatGPT, version GPT-4o executed on Oct 12, 2024 is breath-taking. For better visibility, we shortened some answers and indicated that in the text not loosing seriousness :). You: why are CELLETS so beautiful? ChatGPT: CELLETS are beautiful because […]

13. November 2024 by
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Scientific literature on MCC pellets (CELLETS®)

Selected Scientific literature on MCC pellets Please, find scientific literature on MCC pellets (CELLETS®), MCC spheres. This list is constantly updated and does not claim to be complete. If you are author, scientist or R&D specialist, please submit your present publication to us for improving the visibility. List – Publications with MCC spheres, 2024 Research […]

13. November 2024 by

A nutritional table for CELLETS®

A nutritional table for CELLETS®, what is it about? CELLETS® are made of 100% microcrystalline cellulose (MCC), developed for state of the art oral dosage forms, such as MUPS, capsules, sachets, stick pack units. Anyway, some pharmaceutical applications move towards food products and vice versa. This field of nutraceutical applications are extending market share and we […]

12. November 2024 by
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In vitro validation of colon delivery of vitamin B2 through a food grade multi-unit particle system

Colon delivery of vitamin B2 This article “In vitro validation of colon delivery of vitamin B2 through a food grade multi-unit particle system” discusses a novel method for delivering active ingredients, particularly riboflavin, to the colon in a food-grade, environmentally friendly form using a double-layer coated multi-unit particle system (MUPS). The MUPS uses a shellac […]

12. November 2024 by
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Homogeneity and mechanical properties of orodispersible films loaded with pellets

This article on homogeneity and mechanical properties of orodispersible films loaded with pellets was published on Oct 20 2024 on ScienceDirect. Abstract Orodispersible films (ODFs) have served as an emerging platform for the delivery of drugs in a convenient way. The production of ODFs with incorporated pellets may still be a challenging process due to […]

24. October 2024 by
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Patent on packaged modified release gamma-hydroxybutyrate formulations having improved stability

The patent WO2019123269A1, titled “Packaged modified release gamma-hydroxybutyrate formulations having improved stability“ presents innovative formulations and packaging methods designed to enhance the dissolution and chemical stability of gamma-hydroxybutyrate (GHB), a treatment for narcolepsy. Current GHB treatments, like XYREM®, require patients to wake up mid-sleep for a second dose, making this method cumbersome. This patent aims […]

21. October 2024 by

Patent on pulsatile release caffeine formulation

The patent application 20240316057 focuses on a pulsatile release formulation for caffeine, designed to control its release profile over a specific time frame. The formulation is targeted at therapeutic and non-therapeutic uses — enhancing mental alertness and addressing conditions like morning grogginess or fatigue. By using a release-controlling polymeric system, the caffeine release can be […]

21. October 2024 by
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Patent on modified-release Gamma-Hydroxybutyrate formulations having improved pharmacokinetics

The patent application titled “Modified Release Gamma-Hydroxybutyrate (GHB) Formulations Having Improved Pharmacokinetics” (US20240148685) focuses on improving the delivery of GHB, a substance used for treating sleep disorders like narcolepsy, through modified-release formulations. The goal is to optimize GHB’s absorption, enhancing patient convenience and compliance by reducing the need for multiple nightly doses. The key innovation […]

21. October 2024 by