Entries by Bastian Arlt

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Scientific Literature on MCC Pellets: Insights into CELLETS®

Research Advances in MCC Pellet Technology and Applications Scientific literature on MCC pellets highlights the growing importance of CELLETS® in pharmaceutical and scientific research. These microcrystalline cellulose spheres play a key role in developing reliable multiparticulate drug delivery systems. Researchers have investigated improved rivaroxaban dissolution, efficient film coating kinetics, and their use in orally disintegrating […]

15. June 2026 by
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Delayed release oral pharmaceutical compositions: scientific background, patent insights, and future potential

Introduction to delayed release oral pharmaceutical compositions Delayed release oral pharmaceutical compositions enable drug delivery at a defined time after oral administration. Unlike immediate release dosage forms, these systems control when the active pharmaceutical ingredient becomes available for absorption. As a result, they protect acid-sensitive drugs and allow targeted delivery to specific gastrointestinal regions. Moreover, […]

2. April 2026 by
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Chewable formulations with MCC starter cores

Chewable formulations with MCC starter cores: Patient-centric design and pharmaceutical relevance Chewable formulations with MCC starter cores are an advanced oral dosage form that combines patient-friendly administration with robust pharmaceutical performance. Thereby, patient refers includes humans and non-human mammalian animals, such as dogs, cats, mice, rats, guinea pigs, rabbits, ferrets, cows, horses, sheep, goats, and […]

17. March 2026 by
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Soft tabletting of pellets into Multiple Unit Pellet Systems (MUPS)

Introduction to soft tabletting of pellets and MCC pellet functionality Soft tabletting of pellets is a specialized pharmaceutical compaction approach that enables the compression of coated pellet subunits into tablets while preserving pellet integrity and drug release performance. In this context, Multiple Unit Pellet Systems, or MUPS, combine the biopharmaceutical advantages of multiparticulates with the […]

16. March 2026 by
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Particle Size Distributions of Inert Spheres: Introduction and Summary

Introduction to Particle Size Distributions of Inert Spheres and Their Role in Pelletized Pharmaceutical Products In pharmaceutical formulation science, Particle Size Distributions of Inert Spheres represent a fundamental quality attribute for multiparticulate dosage forms. Inert spheres, such as microcrystalline cellulose pellets, act as neutral carriers for active pharmaceutical ingredients. They enable precise drug layering, predictable […]

16. March 2026 by

Pharmaceutical Starter Cores For Scalable Solutions in Pharma

CELLETS® Pharmaceutical Starter Cores for Pellets & Functional Coatings CELLETS® are high-purity pharmaceutical starter cores. They combine spherical geometry with narrow particle size distribution and defined density. They provide reproducible carriers for functional coatings and enable controlled layer formation in fluid bed and drum coating processes. Thanks to their uniform geometry, CELLETS® ensure stable fluidization, […]

4. March 2026 by
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Different pelletization techniques: Introduction and Summary of the Thesis by Azza A. K. Mahmoud

Introduction to Different Pelletization Techniques and Their Functionality in Drug Formulations Different pelletization techniques form a core part of pharmaceutical manufacturing for solid dosage forms that deliver active pharmaceutical ingredients (APIs) with enhanced performance. Pelletization, a process that generates small, uniform spherical particles, improves flow properties, enables controlled or delayed release, and reduces local irritation […]

11. December 2025 by
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Patent on enzyme-cleavable methadone prodrugs and methods of use thereof

Enzyme‑cleavable methadone prodrugs: Functionality, Opportunities, and Summary of US20250361205A1 Introduction to Enzyme‑cleavable methadone prodrugs Enzyme‑cleavable methadone prodrugs represent a novel class of pharmacological agents designed to provide controlled release of methadone only after specific enzymatic activation. These prodrugs attach an enzyme‑cleavable promoiety to the methadone molecule, rendering it inactive until a target enzyme cleaves the […]

11. December 2025 by

Cellulose-Derived Spherical Activated Carbon

Cellulose-derived spherical activated carbon is a sustainable carbon material made from renewable cellulose sources. It forms uniform spheres with high surface area and excellent porosity after activation. Because of its spherical shape, this carbon flows smoothly, packs efficiently, and resists dust formation. These traits make it ideal for pharmaceutical and biomedical uses. In drug formulation, […]

10. November 2025 by