Entries by Bastian Arlt

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Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form

Introduction to Multilayered Pharmaceutically Active Compound Technology Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form represent an innovative approach to oral drug delivery. This technology combines the benefits of coated pellets with the convenience of liquid administration. Effervescent tablets are solid dosage forms that release carbon dioxide when they dissolve in water. This […]

21. July 2026 by

Formulation and design of multiunit particulate systems

Introduction to the Formulation and Design of Multiunit Particulate Systems Formulation and design of multiunit particulate systems focus on oral dosage forms that contain many small, functional subunits instead of one single unit. These systems typically consist of pellets, granules, or coated spheres that are filled into capsules or compressed into tablets. As a result, […]

21. July 2026 by
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Influence of Water on the Structure of MCC

Influence of Water on the Structure of MCC Influence of Water on the Structure of MCC describes how moisture reshapes microcrystalline cellulose at both structural and dielectric levels [1]. Water interacts strongly with hydroxyl groups on cellulose chains. Therefore, it changes hydrogen bonding and mobility inside amorphous and crystalline regions. Moreover, the system develops distinct […]

21. July 2026 by
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MCC pellets under rheological investigation

MCC pellets under rheological investigation MCC pellets under rheological investigation are ideal model spheres for studying powder behavior. In this study, we revisit the work of V. Mohylyuk and R. Dattani to analyze the effect of pellet size on powder properties. Understanding how pellet size influences flow and handling is essential for optimizing powder performance. […]

21. July 2026 by
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Scientific Literature on MCC Pellets: Insights into CELLETS®

Research Advances in MCC Pellet Technology and Applications Scientific literature on MCC pellets highlights the growing importance of CELLETS® in pharmaceutical and scientific research. These microcrystalline cellulose spheres play a key role in developing reliable multiparticulate drug delivery systems. Researchers have investigated improved rivaroxaban dissolution, efficient film coating kinetics, and their use in orally disintegrating […]

15. June 2026 by
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Delayed release oral pharmaceutical compositions: scientific background, patent insights, and future potential

Introduction to delayed release oral pharmaceutical compositions Delayed release oral pharmaceutical compositions enable drug delivery at a defined time after oral administration. Unlike immediate release dosage forms, these systems control when the active pharmaceutical ingredient becomes available for absorption. As a result, they protect acid-sensitive drugs and allow targeted delivery to specific gastrointestinal regions. Moreover, […]

2. April 2026 by
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Chewable formulations with MCC starter cores

Chewable formulations with MCC starter cores: Patient-centric design and pharmaceutical relevance Chewable formulations with MCC starter cores are an advanced oral dosage form that combines patient-friendly administration with robust pharmaceutical performance. Thereby, patient refers includes humans and non-human mammalian animals, such as dogs, cats, mice, rats, guinea pigs, rabbits, ferrets, cows, horses, sheep, goats, and […]

17. March 2026 by
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Soft tabletting of pellets into Multiple Unit Pellet Systems (MUPS)

Introduction to soft tabletting of pellets and MCC pellet functionality Soft tabletting of pellets is a specialized pharmaceutical compaction approach that enables the compression of coated pellet subunits into tablets while preserving pellet integrity and drug release performance. In this context, Multiple Unit Pellet Systems, or MUPS, combine the biopharmaceutical advantages of multiparticulates with the […]

16. March 2026 by
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Particle Size Distributions of Inert Spheres: Introduction and Summary

Introduction to Particle Size Distributions of Inert Spheres and Their Role in Pelletized Pharmaceutical Products In pharmaceutical formulation science, Particle Size Distributions of Inert Spheres represent a fundamental quality attribute for multiparticulate dosage forms. Inert spheres, such as microcrystalline cellulose pellets, act as neutral carriers for active pharmaceutical ingredients. They enable precise drug layering, predictable […]

16. March 2026 by

Pharmaceutical Starter Cores For Scalable Solutions in Pharma

CELLETS® Pharmaceutical Starter Cores for Pellets & Functional Coatings CELLETS® are high-purity pharmaceutical starter cores. They combine spherical geometry with narrow particle size distribution and defined density. They provide reproducible carriers for functional coatings and enable controlled layer formation in fluid bed and drum coating processes. Thanks to their uniform geometry, CELLETS® ensure stable fluidization, […]

4. March 2026 by