Entries by Bastian Arlt

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Hot-Melt Coating Materials: Enhancing Pharmaceutical and Industrial Applications

Hot-melt coating materials improve efficiency and product quality in pharmaceutical and industrial manufacturing. They melt when heated and solidify quickly, forming strong, uniform coatings on various surfaces. As a result, manufacturers reduce production time, lower costs, and avoid using solvents. Furthermore, understanding wetting behavior and delamination is critical to optimize coating performance. For example, CELLETS® […]

18. August 2025 by
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Patent on hydroxynorketamine modified‑release dosage form for the use in the treatment of depression

Introduction The development of a hydroxynorketamine modified-release dosage form marks an important advance in neuropsychiatric therapy. Hydroxynorketamine (HNK), a ketamine metabolite, shows rapid antidepressant activity through mechanisms different from ketamine itself. It works mainly by modulating α7-nicotinic acetylcholine receptors and activating mTOR pathways. This targeted action makes HNK a strong candidate as an active pharmaceutical […]

11. July 2025 by
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Patent on methods of administering gamma-hydroxybutyrate compositions with divalproex sodium

Introduction Gamma‑hydroxybutyrate (GHB) is an endogenous neurotransmitter also used pharmaceutically—usually as sodium oxybate—for treating narcolepsy and related disorders. It exerts its therapeutic effects by modulating GABA_B receptors and promoting slow-wave sleep, alleviating cataplexy, and reducing excessive daytime sleepiness. Despite its efficacy, current twice-nightly dosing regimens present challenges: dose‑dumping in the presence of alcohol, variable pharmacokinetics […]

11. July 2025 by
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Scientific Literature on MCC Pellets: Insights into CELLETS®

Research Advances in MCC Pellet Technology and Applications Scientific literature on MCC pellets highlights the growing importance of CELLETS® in pharmaceutical and scientific research. These microcrystalline cellulose spheres play a key role in developing reliable multiparticulate drug delivery systems. Researchers have investigated improved rivaroxaban dissolution, efficient film coating kinetics, and their use in orally disintegrating […]

9. July 2025 by
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A regenerable microporous adsorbent based on microcrystalline cellulose for organic pollutants adsorption

Introduction Fixed-bed column adsorption is an essential process in modern water treatment systems, widely implemented due to its continuous operation, ease of design, and applicability in large-scale systems. In this method, a contaminant-laden liquid passes through a column packed with adsorbent material, facilitating efficient contaminant removal before discharge or reuse. While effective for many pollutants, […]

9. July 2025 by
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Cellulose CELLETS as new type of adsorbent for the removal of dyes from aqueous media

Abstract CELLETS, a new type of adsorbent, have emerged as a promising solution in water treatment. They are particularly effective in fixed-bed column systems for removing persistent organic pollutants, such as synthetic dyes. This summary reflects research published by Suteu et al. [1]. Fixed-bed adsorption is a well-established filtration method. It allows continuous treatment of […]

8. July 2025 by
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Renewable Resource Biosorbents: Granulated Cellulose CELLETS 200 for Organic Pollutants Adsorption in Fixed-Bed Column Systems

Introduction Fixed-bed column techniques are widely applied in water and wastewater treatment to achieve continuous adsorption of pollutants. In these systems, aqueous effluent flows through a packed bed of adsorbent material, offering operational simplicity, easy scale-up, and consistent performance—critical features in industrial and pharmaceutical settings. However, removing dyes from pharmaceutical effluents presents unique challenges: dyes […]

8. July 2025 by
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Fixed-bed-column studies for methylene blue removal by CELLETS

This study investigated fixed-bed columns for methylene blue removal. It evaluated CELLETS®, a granulated spherical cellulose material, as an adsorbent in the system [1]. CELLETS® 200 has useful properties, including perfect sphericity, narrow particle size distribution, low friability, and chemical inertness. Experiments used a dye solution (9–10 mg/L, pH 4.7) with different flow rates. We […]

7. July 2025 by

Ultrasound Imaging of Artificial Tongues – an approach with Cellets

The article titled “Ultrasound Imaging of Artificial Tongues During Compression and Shearing of Food Gels on a Biomimetic Testing Bench” by Glumac et al. [1] introduces a novel method to study tongue–food interactions using ultrasound (US) imaging. The study primarily aims to improve understanding of mechanical processes during oral food processing. In particular, it focuses on […]

13. June 2025 by