Case Studies

cellulose-derived spherical activated carbon

Cellulose-Derived Spherical Activated Carbon

Cellulose-derived spherical activated carbon is a sustainable carbon material made from renewable cellulose sources. It forms uniform spheres with high surface area and excellent porosity after activation. Because of its spherical shape, this…
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Characterization of Layered Pellets containing amorphized amlodipine besylate and hydrochlorothiazide

Characterization of Layered Pellets and the Role of Amorphized Amlodipine Besylate / Hydrochlorothiazide

Characterization of layered pellets forms the basis of advanced pharmaceutical pellet design. These pellets consist of inert cores coated with active drug layers. Their detailed analysis ensures uniformity, strength, and consistent drug release.…
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cellulose-derived spherical activated carbon
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Cellulose-derived spherical activated carbon – sustainable nanoarchitectonics for efficient uremic toxin removal in pharmaceutical applications

Cellulose-Derived Spherical Activated Carbon Cellulose-derived spherical activated carbon offers a sustainable and efficient solution for adsorbing harmful compounds such as uremic toxins [1]. This carbon material is made from renewable cellulose,…
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Explore how the Multiple-Unit Pellet System with Diclofenac Sodium
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Multiple-Unit Pellet System with Diclofenac Sodium

Multiple-Unit Pellet System with Diclofenac Sodium represents a modern and flexible approach to oral drug delivery. This multiparticulate system divides the drug dose into many small pellets, each functioning as an individual unit. Because of…
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Cellets list of publication
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Scientific Literature on MCC Pellets: Insights into CELLETS®

Research Advances in MCC Pellet Technology and Applications Scientific literature on MCC pellets highlights the growing importance of CELLETS® in pharmaceutical and scientific research. These microcrystalline cellulose spheres play a key role…
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Multiparticulate Oral Dosage Form of Tapentadol
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Multiparticulate Oral Dosage Form of Tapentadol

Multiparticulate oral dosage form of tapentadol introduces a modern way to control drug release and improve pain management. The invention, described in patent US20250295596A1, replaces traditional monolithic extended-release tablets with numerous…
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UV Imaging of MUPS Tablets Stability, Functionality, and Outcomes
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UV Imaging of MUPS Tablets: Stability, Functionality, and Outcomes

Introduction to UV Imaging of MUPS Tablets UV imaging of MUPS tablets (multiple unit pellet system) is a growing field in pharmaceutical research. These tablets combine many coated pellets into one compressed unit. After ingestion, the tablet…
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CELLETS® in Malodor Control Compositions

CELLETS® in Malodor Control Compositions: A Patent Overview

Introduction to Malodor Control Technology CELLETS® in malodor control compositions mark a new step in odor management. Unpleasant smells from sulfur compounds, volatile organic compounds, aldehydes, and acids are often hard to control. Even…
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Delamination and wetting behavior of natural hot-melt coating materials
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Hot-Melt Coating Materials: Enhancing Pharmaceutical and Industrial Applications

Hot-melt coating materials improve efficiency and product quality in pharmaceutical and industrial manufacturing. They melt when heated and solidify quickly, forming strong, uniform coatings on various surfaces. As a result, manufacturers reduce…
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hydroxynorketamine modified-release dosage form ChatGPT Image 11. Juli 2025, 13_57_57
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Patent on hydroxynorketamine modified‑release dosage form for the use in the treatment of depression

Introduction The development of a hydroxynorketamine modified-release dosage form marks an important advance in neuropsychiatric therapy. Hydroxynorketamine (HNK), a ketamine metabolite, shows rapid antidepressant activity through mechanisms…
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US20250186377A1 cellet‑based modified‑release gamma‑hydroxybutyrate formulation ChatGPT Image 11. Juli 2025, 13_12_09
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Patent on methods of administering gamma-hydroxybutyrate compositions with divalproex sodium

Introduction Gamma‑hydroxybutyrate (GHB) is an endogenous neurotransmitter also used pharmaceutically—usually as sodium oxybate—for treating narcolepsy and related disorders. It exerts its therapeutic effects by modulating GABA_B receptors…
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microcrystalline cellulose for organic pollutants adsorption
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A regenerable microporous adsorbent based on microcrystalline cellulose for organic pollutants adsorption

Introduction Fixed-bed column adsorption is an essential process in modern water treatment systems, widely implemented due to its continuous operation, ease of design, and applicability in large-scale systems. In this method, a contaminant-laden…
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CELLETS as new type of adsorbent
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Cellulose CELLETS as new type of adsorbent for the removal of dyes from aqueous media

Abstract CELLETS, a new type of adsorbent, have emerged as a promising solution in water treatment. They are particularly effective in fixed-bed column systems for removing persistent organic pollutants, such as synthetic dyes. This summary…
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Cellets 200 for organic pollutants adsorption
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Renewable Resource Biosorbents: Granulated Cellulose CELLETS 200 for Organic Pollutants Adsorption in Fixed-Bed Column Systems

Introduction Fixed-bed column techniques are widely applied in water and wastewater treatment to achieve continuous adsorption of pollutants. In these systems, aqueous effluent flows through a packed bed of adsorbent material, offering operational…
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Fixed-bed-column studies for methylene blue removal by CELLETS
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Fixed-bed-column studies for methylene blue removal by CELLETS

This study investigated fixed-bed columns for methylene blue removal. It evaluated CELLETS®, a granulated spherical cellulose material, as an adsorbent in the system [1]. CELLETS® 200 has useful properties, including perfect sphericity, narrow…
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Ultrasound Imaging of Artificial Tongues – an approach with Cellets

Ultrasound Imaging of Artificial Tongues – an approach with Cellets

The article titled "Ultrasound Imaging of Artificial Tongues During Compression and Shearing of Food Gels on a Biomimetic Testing Bench" by Glumac et al. [1] introduces a novel method to study tongue–food interactions using ultrasound (US)…
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Patent on solid oral dosage form comprising antibodies for sustained release in the lower gastrointestinal tract (ChatGPT-Image-6.-Mai-2025-16_09_21 Kopie)

Patent on solid oral dosage form comprising antibodies for sustained release in the lower gastrointestinal tract

Abstract The patent "Solid oral dosage form comprising antibodies for sustained release in the lower gastrointestinal tract" (US20250127722A1 [1]) presents a novel pharmaceutical formulation. It uses microcrystalline cellulose pellets, called…
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Real-time monitoring of multiparticulate coating processes
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Real-time monitoring of multiparticulate coating processes at industrial-scale using ultra-high-resolution optical coherence tomography

Real-time monitoring of multiparticulate coating processes at industrial-scale is a critical demand for continuous and batch-wise process technologies. A combination with ultra-high-resolution optical coherence tomography is indeed a brilliant…
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Theophylline size distribution
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Patent on oral formulations of a Pyridinone derivate

Abstract This patent describes an oral formulation designed to deliver a drug (a Pyridinone derivative) specifically to the small intestine. The formulation contains coated granules, pellets, beads, minicapsules, or minitablets. Each particle…
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Patent on enteric-coated particles containing lactoferrinAdobe Firefly
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Patent on enteric-coated particles containing lactoferrin

Abstract The present invention generally relates to enteric-coated particles containing lactoferrin. More specifically, the present invention provides an enteric-coated particle comprising (or consisting essentially of): a) a core comprising…
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Revealing the physical restrictions of caecal influx in broilers through the use of solid and soluble markers
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Revealing the physical restrictions of caecal influx in broilers through the use of solid and soluble markers

Abstract A promising strategy to support broiler health and performance in a sustainable way is the enhancement of microbial fibre fermentation in broilers. This fermentation mainly occurs in the caeca, but the actual particle size range…
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Conclusion of the Blog Seriesadobe firefly

Conclusion of the Blog Series: Innovations in Controlled Drug Release

Over the past few weeks, we have explored the fascinating world of patents related to controlled and modified drug release through our eight-part blog series. This journey has taken us from the extended release of pyridostigmine and atomoxetine…
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US20240350420A1 methods for treating hyperhidrosis
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Patent on pharmaceutical compositions and methods for treating hyperhidrosis

The patent application US20240350420A1 focuses on pharmaceutical formulations and methods for treating conditions such as hyperhidrosis, which causes excessive sweating. It details the development of modified-release compositions using Pilocarpine…
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US20240350437A1 Patent on gamma-hydroxybutyrate compositions
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Patent on gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state

Patents US20240350437A1 and US20240350438A1 - Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state – cover pharmaceutical compositions and systems that deliver oral drugs in a controlled and consistent way.…
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What does AI say about Cellets

What does AI say about CELLETS?

Did you ever wonder, what AI engines say about CELLETS? Artificial Intelligence engines answers by example of ChatGPT, version GPT-4o executed on Oct 12, 2024 is breath-taking. For better visibility, we shortened some answers and indicated that…
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nutritional table for CELLETS®

A nutritional table for CELLETS®

What is a nutritional table for CELLETS® about? CELLETS® consist of 100% microcrystalline cellulose (MCC) and were developed for advanced oral dosage forms, such as MUPS, capsules, sachets, and stick pack units. Some pharmaceutical applications…
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In vitro validation of colon delivery of vitamin B2 through a food grade multi-unit particle system
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In vitro validation of colon delivery of vitamin B2 through a food grade multi-unit particle system

Colon Delivery of Vitamin B2: A Novel Food-Grade Approach Innovative Food-Grade Delivery Systems This article, "In vitro validation of colon delivery of vitamin B2 through a food grade multi-unit particle system," [1] presents a novel method…
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Homogeneity and mechanical properties of orodispersible films loaded with pellets
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Homogeneity and mechanical properties of orodispersible films loaded with pellets

Orodispersible films loaded with pellets provide a convenient and patient-friendly approach for drug administration. They dissolve quickly in the mouth, eliminating the need for water and making them ideal for children, elderly patients, and…
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packaged modified release gamma-hydroxybutyrateadobe firefly
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Patent on packaged modified release gamma-hydroxybutyrate formulations having improved stability

Packaged modified release gamma-hydroxybutyrate formulations improve stability and simplify treatment. The patent WO2019123269A1, titled "Packaged modified release gamma-hydroxybutyrate formulations having improved stability," introduces innovative…
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pulsatile release caffeine formulationadobe firefly

Patent on pulsatile release caffeine formulation

The patent application 20240316057 focuses on a pulsatile release formulation for caffeine, designed to control its release profile over a specific time frame. The formulation is targeted at therapeutic and non-therapeutic uses — enhancing…
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Modified release Gamma-Hydroxybutyrateadobe firefly
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Patent on modified-release Gamma-Hydroxybutyrate formulations having improved pharmacokinetics

The patent application titled "Modified Release Gamma-Hydroxybutyrate (GHB) Formulations Having Improved Pharmacokinetics" (US20240148685) focuses on improving the delivery of GHB, a substance used for treating sleep disorders like narcolepsy,…
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highly lipophilic physiologically activeadobe firefly
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Patent on controlled release formulations of highly lipophilic physiologically active substances

The patent application US20240139215A1 focuses on the development of controlled release formulations for highly lipophilic physiologically active substances, such as cannabinoids. These substances tend to have high lipid solubility (log P of…
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methods of administering gamma-hydroxybutyrateadobe firefly
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Patent on methods of administering gamma-hydroxybutyrate compositions with divalproex sodium

The United States Patent Application US20240024263 focuses on methods of administering gamma-hydroxybutyrate (GHB) in combination with divalproex sodium (DVP), particularly for treating conditions like narcolepsy. The aim is to co-administer…
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Modified release gamma-hydroxybutyrateadobe firefly
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Patent on modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics

The development of modified release gamma-hydroxybutyrate represents a major advancement in narcolepsy therapy, aiming to improve both patient compliance and treatment effectiveness. Traditional formulations of gamma-hydroxybutyrate (GHB) require…
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Extended release compositions comprising pyridostigmine

Patent on extended release compositions comprising pyridostigmine

The following patent on "Extended release compositions comprising pyridostigmine" employs CELLETS® as starter spheres made of Microcrystalline Cellulose. Please, read below a summary. US Patent 20240299305 addresses an extended-release…
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Extended-release compositions comprising atomoxetine
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Patent on Extended-release compositions comprising atomoxetine

The following patent on "Extended-release compositions comprising atomoxetine" employs CELLETS® as starter spheres made of Microcrystalline Cellulose. Please, read below a summary. United States Patent Application 20240299307 focuses on…
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Influence of Polymer Film Thickness on Drug Release from Fluidized Bed Coated Pellets

Influence of Polymer Film Thickness on Drug Release from Fluidized Bed Coated Pellets and Intended Process and Product Control

This article "Influence of Polymer Film Thickness on Drug Release from Fluidized Bed Coated Pellets and Intended Process and Product Control" was published on Pharmaceutics 2024, 16(10), 1307; https://doi.org/10.3390/pharmaceutics16101307,…
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Firefly How to improve the dissolution performance of rivaroxaban. 18547 example image

How to improve the dissolution performance of rivaroxaban?

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fig-3_Plasticity of Microcrystalline Cellulose Spheres
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The Increase in the Plasticity of Microcrystalline Cellulose Spheres’ When Loaded with a Plasticizer

Abstract Compaction pressure can induce an undesirable solid-state polymorphic transition in drugs, fragmentation, loss of coated pellet integrity, and the decreased viability and vitality of microorganisms. Thus, the excipients with increased…
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Pellets Overview Technologies (small)Glatt
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Titelbild Brezovar-2023
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The Effect of Design and Size of the Fluid-Bed Equipment on the Particle Size-Dependent Trend of Particle Coating Thickness and Drug Prolonged-Release Profile

Abstract The focus of the current work is to study and demonstrate the impact of the design, the scale, and settings of fluid-bed coating equipment on the differences in pellet coating thickness, which in case of prolonged-release pellets…
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Continuous Manufacturing of Cocrystals Using 3D-Printed Microfluidic Chips Coupled with Spray Coating
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Continuous Manufacturing of Cocrystals Using 3D-Printed Microfluidic Chips Coupled with Spray Coating

Abstract on Continuous Manufacturing Using cocrystals has emerged as a promising strategy to improve the physicochemical properties of active pharmaceutical ingredients (APIs) by forming a new crystalline phase from two or more components.…
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Modelling the disintegration of pharmaceutical tablets
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Modelling the disintegration of pharmaceutical tablets: integrating a single particle swelling model with the discrete element method

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Development of a New Bioequivalent Omeprazole Productingredientpharm
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Development of a New Bioequivalent Omeprazole Product

The publication by G. Kumisbek, D. Vetchý, A. Kadyrbay describes gently the development and implementation of a new generic enteric form of CELLETS® 700 (MCC pellets, 700-1000 µm) loaded with omeprazole in capsules by Viva Pharm LLP, a pharmaceutical…
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Paediatric solid oral dosage forms for combination products: Improving in vitro swallowability of minitablets using binary mixtures with pellets
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Paediatric solid oral dosage forms for combination products: Improving in vitro swallowability of minitablets using binary mixtures with pellets

Abstract on paediatric solid oral dosage forms There is a growing interest in enhancing the acceptability of paediatric pharmaceutical formulations. Solid oral dosage forms (SODF), especially multiparticulates, are being considered as an…
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Comparison of Mini-Tablets and Pellets as Multiparticulate Drug Delivery Systems for Controlled Drug Release
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Comparison of Mini-Tablets and Pellets as Multiparticulate Drug Delivery Systems for Controlled Drug Release

Multiparticulate Drug Delivery Systems: Advantages and Applications Multiparticulate drug delivery systems offer clear advantages for controlled drug release. Manufacturers can place mini-tablets in hard capsules or administer them using special…
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Theophylline size distribution

Investigating the Influence of Fluid-Bed Equipment Design and Size on Particle Coating Thickness Trends and Drug Prolonged-Release Profiles Linked to Particle Size

The primary objective of this research is to investigate the design and size on particle coating thickness. Furthermore,  illustrate how the design, size, and configurations of fluid-bed coating machinery influence variations in pellet coating…
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Critical aspects of starter spheres in oral pellet formulations one should consideringredientpharm
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Critical aspects of starter spheres in oral pellet formulations one should consider

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Preparation and characterization of controlled-release doxazosin mesylate pelletsingredientpharm

Preparation and characterization of controlled-release doxazosin mesylate pellets using a simple drug layering-aquacoating technique

Abstract Pellets are one of multiparticulate pharmaceutical forms and can offer numerous technical and biopharmaceutical advantages compared with single dose unit formulations, e.g. tablets and capsules. This study aimed at formulation…
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Pore Former basic drugs

Design and Optimization of a Nanoparticulate Pore Former as a Multifunctional Coating Excipient for pH Transition-Independent Controlled Release of Weakly Basic Drugs for Oral Drug Delivery

Abstract Bioavailability of weakly basic drugs may be disrupted by dramatic pH changes or unexpected pH alterations in the gastrointestinal tract. Conventional organic acids or enteric coating polymers cannot address this problem adequately…
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Amorphous Solid Dispersions Layered onto Pellets - An Alternative to Spray Drying

Amorphous Solid Dispersions Layered onto Pellets – An Alternative to Spray Drying?

This article "Amorphous Solid Dispersions Layered onto Pellets - An Alternative to Spray Drying?" is an excerpt from the publication of Neuwirth et al., Pharmaceutics 2023, 15(3), 764; https://doi.org/10.3390/pharmaceutics15030764. Abstract Spray…
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Benefits of multilayer high drug-loaded amorphous solid dispersions

Benefits and challenges of multilayer high drug-loaded amorphous solid dispersions

Introduction on amorphous solid dispersions What is the benefit of multilayer amorphous solid dispersions? Recently, several studies had been performed on amorphous solid dispersions working spheres or starter beads. Starter beads, such as…
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Amorphous solid dispersions at various aspects part 2ingredient pharm

Amorphous solid dispersions at various aspects

Amorphous solid dispersions play an essential role in modern pharmaceutical research. They improve the solubility and dissolution rate of poorly water-soluble drugs, and therefore they gain more importance in drug development. Although several…
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titelbild - Hydrodynamic behavior of MCC Spheres in a spouted bedingredientpharm
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Hydrodynamic behavior of MCC Spheres in a spouted bed

Abstract This case study is a short abstract on spouted bed characteristics, following closely findings in the publication by J. Vanamu and A. Sahoo [1]. Spouted bed systems are of highest importance for all powder processing industries,…
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muliparticulates-titleingredientpharm

Coating weight gain and API release in multiparticulates

Abstract Multiparticulates made of pellets are ideal dosage forms to be used in pediatrics. Having the suitability of paediatric consumers in mind, formulations of small-sized pellets offer a valuable base for increased compliance and improved…
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Metoprolol pellets

Metoprolol Tartrate: controlled release drug layered pellets for colon-specific drug delivery

Abstract on Metoprolol pellets Metoprolol Tartrate is a salt of Metoprolol, a selective β1-receptor blocker medication. The application is the treatment of high blood pressure, chest pain due to poor blood flow to the heart, and several conditions…
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Figure 3: SEM picture of cross section of a Taste masked pellets coated with 25 mg Eudragit EPO.
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Atomoxetine HCl Pellets in MUPS Formulations

Abstract This case study on Atomoxetine HCl pellets is a short abstract of the publication by Y.D. Priya et al. [1]. Atomoxetine is a medication used to treat attention deficit hyperactivity disorder (ADHD) [2]. The API is marketed under…
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Taste masked coated micropellets
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Tamoxifen citrate was spray layered micropellets for Cre recombination research

Abstract on Tamoxifen Tamoxifen is widely used in transgenic research in mice to induce Cre recombinase activity and achieve conditional gene knockouts [1]. However administrating tamoxifen to mice is challenging The commonly used dosing methods…
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Advantages of technological methods compared to a pure API usage.Ingredient Pharm
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Technologies for enhancing bioavailability of Simvastatin

Abstract This application note is based on content from Pohlen et al. [1]. Simvastatin (CAS number 79902-63-9) is a cholesterol-lowering agent with a low bioavailability of 5% [2,3]. This API is formulated as a lipid based drug delivery system…
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Close-up SEM images of Cellets® 500 particles coated with sodium benzoate at process conditions as printed in Table 2 (bold).

Multidimensional Correlation of Surface Smoothness and Process Conditions

Abstract Multidimensional Correlation of Surface Smoothness and Process Conditions is a necessary attempt to better understand, optimize and outperform process steps of drug formulations. Particle coating and layering in a fluidized bed process…
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Figure 4: Images of a Jelly without (left) and with incorporation of sustained release micropellets (right).

Gliclazide formulations for Sustained Release Delivery

Abstract Patients with dysphagia may have obstacles to swallow tablets or large multiparticulates. The former dosage form can even not be crushed in case that the tablet exhibits a modified release or taste-masking profile through outer layering.…
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Figure 2: SEM image of drug loaded and coated starter beads. Particles show a high level of homogeneity in size distribution.

Microparticle coating in Wurster Fluidized Bed – Scalable Production of Oral Sustained-Release Drugs

Abstract Modified drug release formulations for suspensions are a perfect solution for children and patients with swallowing difficulties. In many cases, these formulations are based on pellets serving as starter beads. In this report, an attempt…
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Coating uniformity of hot-melt coated particles Figure 2 (pure)

Coating uniformity of hot-melt coated particles

Abstract Coating uniformity is a critical parameter in coating processes in novel pharmaceutical formulations. Speaking about pellet technology, coating and layering are the main methods for implementing drug functionalities, such as modified…
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Fig. 3: Dissolution as a function of time. Black: ASD layered pellets (FB). Red: ASD pellets from direct pelletization (SB). Blue: physical mixture.

Amorphous solid dispersions layered pellets

Abstract Amorphous solid dispersions layered pellets solve a problem of poorly water soluble drugs. Speaking about oral drug formulations, drug carrier solutions based on starter cores are suitable for several drug classes and open new opportunities…
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Figure-3Ingredientpharm
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Impact of the particle size on powder behavior in a Wurster fluid-bed process

Abstract Cellets are inert starter cores made of microcrystalline cellulose (MCC). They play an important role in new formulations of solid dosage forms. As a carrier system for actives, the chemical inertness and surface smoothness are crucial…
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Pellets and micropellets can be further processed into a wide rangeglatt.com
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The path to the perfect sphere

The renaissance of micropellets is promoting innovative technologies In recent years, formulations based on pellets and micropellets have been the trend. New technologies make it possible to circumvent property rights for active ingredients…
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Cellets_350-1-3ingredientpharm
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Some light on sugar and microcrystalline cellulose pellets

Abstract Microcrystalline cellulose pellets (MCC) and sugar are well-known materials in pellet technology. Pellet technology describes the drug load onto starter pellets for controlled release formulations by Wurster process or others. Inert…
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CS_hydrocortisone_image_5

Case Study: Hydrocortisone for paediatrics

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CS_sphericity_image_1
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Sphericity and size distribution of µm-sized microcrystalline pellets

Abstract Microcrystalline Cellulose (MCC) pellets represent a chemically inert class of active pharmaceutical ingredients (API) carriers. A narrow particle size distribution (PSD) maximizes control over content uniformity. In this case study,…
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CS_taste_image_1

Taste-masked cellulose based pellets for compaction

Abstract Several drug substances are known to be extremely bitter. In special for paediatric and geriatric applications, costumer compliance by means of taste acceptance is a highly sensitive topic. Taste masking is therefore an important issue…
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MUPS_image_4
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Better MUPS tablets: Aspects of MCC starter beads

Abstract Starter beads such as pellets made of microcrystalline cellulose (MCC) are frequently used in the formulation of oral drug delivery systems, e.g. multiparticulates [1] or multi-unit pellet system (MUPS) tablets [2]. Certain properties…
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Theophylline size distribution

Case Study: Layering of Theophylline

Abstract Theophylline is a powerful active used for the acute treatment of respiratory distress. Its bioavailability and uptake rates are high. Drug carrier systems are pellets made of sugar or microcrystalline cellulose (MCC). This case study…
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Introduction to CELLETS® case studies

CELLETS® case studies show how microcrystalline cellulose spheres support pharmaceutical research, nutrition, and drug delivery. These studies highlight the versatility of CELLETS® as starter cores for controlled and modified release. They also demonstrate their role as food-grade carriers and solid markers in biological studies. Therefore, by reviewing CELLETS® case studies, it becomes clear how these particles advance drug targeting, improve pharmaco-kinetics, and enable innovation in both human and animal health.

A list of highly-rated scientific publications

MCC starter beads are frequently used in scientific publications. Main research is established in pharmaceutical applications, but we also identify CELLETS® in non-pharma research activities, such as in nutra, food and cosmetics. Impressively, these pellets help supporting young researchers in publishing their first poster, paper, publication in renowned journals and conferences. See the publication list here.

Recent applications of CELLETS® in pharmaceutical innovations

CELLETS® case studies reveal several pharmaceutical breakthroughs. Patents on pyridinone derivatives and enteric-coated lactoferrin use CELLETS® to deliver active compounds directly to the small intestine. In addition, they shield sensitive ingredients from stomach acid. Research on hyperhidrosis and gamma-hydroxybutyrate (GHB) also shows how CELLETS® enable modified-release systems. Moreover, they improve pharmacokinetics in fed conditions. See more here.

CELLETS® in nutrition and gut health research

CELLETS® case studies also explore nutrition and gut health. A food-grade delivery system with vitamin B2 uses CELLETS® as the foundation for colon-targeted release. As a result, nearly all of the vitamin is released exactly where it benefits gut function most. In addition, CELLETS® offer a safe, stable base for multi-unit particle systems that enhance nutritional therapies. See more here.

Scientific validation and practical insights from CELLETS® case studies

CELLETS® case studies provide strong scientific validation. For instance, in vitro tests confirm their effectiveness in targeted release. Furthermore, research in broilers uses CELLETS® as solid markers to track caecal influx. Comprehensive literature reviews also reinforce their credibility. In addition, nutritional tables and AI-based assessments show CELLETS® are widely accepted as reliable excipients. Consequently, these case studies demonstrate their broad value in pharmaceutical technology and nutrition science. See more here.